Important: Please read the following before attempting to run the CCaLC PVC tool V2.0.

0. This version of the tool, released in August 2011, represents an updated version of V1.1 (released in October 2010). It is fully compatible with versions 1.0 and 1.1 and studies created in the previous versions can be imported easily into this version via the menu option'Share data/Import data'. See the user manual for detailed instructions. 

1. For users of other CCaLC tools:

The CCaLC PVC tool is fully compatible with other CCaLC tools, including CCaLC V2.0 and CCaLC BIOCHEM. Studies created in any of the tools and can be shared via the menu option 'Share data/Export data' or 'Share data/Import data'. See the user manual for detailed instructions.

2. System requirements

The CCaLC PVC tool is an Excel-based application run by macros. It was designed and built using the English-version of Microsoft Excel for Windows XP. The tool may not run properly on non-English operating systems and/or older versions of Windows. CCaLC is designed for use on PCs and is not suitable for use on Mac computers.  


3. Security settings

In order for the CCaLC PVC macros to work correctly, the Excel security settings should be set to either Medium or Low. In Excel 2003, on opening the tool, click on 'Enable macros' when prompted. In Excel 2007 and 2010, on opening the tool, click on 'Security Warning - Options'and select 'Enable this content'.

4. Using Excel version 2007 and 2010

To see the CCaLC PVC menus in Excel 2007 or 2010, click on the Add-ins tab on the main menu-bar. The menu items will be displayed on the left hand side of the main menu-bar. 

When saving the CCaLC PVC tool with your studies, it is IMPORTANT to save it as Excel 97-2003 file type; otherwise, the studies will not be saved. To do this:

In Excel 2007: from the File menu, choose Excel Options/Save and Save as file type: Excel 97-2003 workbook (.xls)

In Excel 2010: from the File menu, choose File/Options/Save and Save as file type: Excel 97-2003 workbook (.xls)

5. CCaLC PVC manual

The manual can be found as a pdf file under the CCaLC Help menu option. 

6. Learning how to use CCaLC PVC

The easiest way to learn how to use the tool is to load one of the built-in case studies and examine/modify them. These are available on the top page of the tool and can be accessed by clicking on any of the coloured boxes provided.

7. Terms and conditions

CCaLC PVC is free of charge. By using the tool, the user accepts the following terms and conditions:
•	To use the tool solely for their own purposes 
•	Not to use the tool for any income-generating consulting services
•	Not to copy or distribute the tool to a third party.


8. Credits

The CCaLC PVC tool was developed by a research group based at the University of Manchester and led by Professor Adisa Azapagic. The project was funded by EPSRC (grant number EP/D505372/2).

CCaLC PVC ©2006-2011. All rights reserved.